Eczema

Eczema is a common skin condition characterized by an itchy, red rash. The rash may come and go. Various triggers may worsen it - stress, cold weather, frequent bathing, etc.. Usually eczema is treated with powerful topical steroids - these may cause many side effects with long term use and natural treatment allows many people to lessen or even avoid the use of these potent medications.

Dietary manipulation:

Eczema may be triggered by allergies, and is more common in people with other allergic disorders like asthma.1 2 Searching for a cause may require some serious detective work, but this may pay off big once the trigger for the allergy has been identified - avoidance of the allergen can lead to significant health improvement.3

When heavy coffee drinkers with eczema avoided their favorite beverage, eczema symptoms were reported to improve.4 In this study, the reaction was to coffee - not caffeine. Using a hypoallergenic diet to investigate food allergies may be useful to check into other sources of allergy.

Nutritional supplements:

Essential Fatty Acids - People with eczema do not have the normal ability to process fatty acids, especially essential fatty acids (EFA's). They are "essential" because we must have them in our diet, they cannot be made by our body. This can result in a deficiency of gamma-linolenic acid (GLA), one of the essential fatty acids.5 GLA is found in evening primrose oil (EPO), borage oil, and black currant seed oil. Most double-blind research has shown that EPO overcomes this block and is useful in the treatment of eczema.6 7 8 The effects for reduced itching are usually most striking.9 Much of the research uses 12 pills per day; each pill containing 500 mg of EPO, of which 45 mg is GLA. One study questioned the effectiveness of evening primrose oil for eczema;10 however, this negative study has been criticized.11 Consistent, reproducible problems from taking evening primrose oil have not been reported, and it is safe to use long term. EFA's seem to have their effect mostly through their anti-inflammatory properties - they enter the same anti-inflammation pathway as the arthritis medications. They benefit not only skin conditions, but also asthma and arthritis!

Soy - The addition of soy to the diet is also very beneficial for the management of eczema. Soy also has a wonderful anti - inflammatory effect because soy "fat" is about 50 percent linoleic acid, another Essential Fatty Acid. A great supplement - you need 30-50 mg of soy per day.

Fish Oil - ten grams of fish oil providing 1.8 grams of EPA (eicosapentaenoic acid) per day were given to a group of eczema sufferers in a double-blind trial. After twelve weeks, those using the fish oil experienced significant improvement.14 According to the researchers, fish oil may be effective because it reduces levels of leukotriene B4, a substance that has been linked to eczema.15 The eczema-relieving effects of fish oil may require taking very large doses. A nutritionally oriented doctor should be consulted before long-term use of more than 3–4 grams of fish oil is contemplated, because a high intake has been reported to sometimes elevate blood sugar, cholesterol, and glucose levels. Side effects from fish oil include nose bleeds (because of reduced blood clotting), gastrointestinal upset, and "fishy" burps.

Vitamin E - 400 IU per day has been reported to alleviate eczema,16 however no formal study has investigated this effect. Vitamin E toxicity is very rare and supplements are widely considered to be safe, yet doses over 800 IU may increase bleeding time. Caution must be exercised by people on other blood thinning medications (Coumadin) or supplements (Ginkgo, Fish oil, etc.).

Vitamin C - In 1989, Medical World News reported that researchers from the University of Texas found that vitamin C, at 50–75 mg per 2.2 pounds of body weight, reduced symptoms of eczema in a double-blind trial.17 Vitamin C may be beneficial in eczema by affecting the immune system. Some individuals develop diarrhea after as little as a few thousand milligrams of vitamin C per day, while others are not bothered by ten times this amount. However, high levels of vitamin C can deplete the body of copper,18 an essential nutrient. It is prudent to ensure adequate copper intake at higher intakes of vitamin C (copper is found in many multivitamin/mineral supplements).

Herbs that may be helpful:

Licorice root, used either internally or topically, may help alleviate symptoms of eczema. A traditional Chinese herbal preparation, which includes licorice, has been successful in treating childhood and adult eczema. The product, known as Zemaphyte, is currently under investigation in England. One or two packets of the combination is mixed in hot water and taken once per day.19 20 Topically, glycyrrhetinic acid, a constituent of licorice root, reduces the inflammation and itching associated with eczema.21

Sarsaparilla may be beneficial as an anti-inflammatory. 

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References:

1. Sampson HA, Scanlon SM. Natural history of food hypersensitivity in children with atopic dermatitis. J Pediatr 1989;115:23–7.
2. Burks AW, Mallory SB, Williams LW, Shirrell MA. Atopic dermatitis: clinical relevance of food hypersensitivity. J Pediatr 1988;113:447–51.
3. Atherton DJ. Diet and atopic eczema. Clin Allerg 1988;18:215–28 [review].
4. Veien NK, Hattel T, Justesen O, et al. Dermatoses in coffee drinkers. Cutis 1987;40:421–2.
5. Manku MS, Horrobin DF, Morse NL, et al. Essential fatty acids in the plasma phospholipids of patients with atopic eczema. Brit J Dermatol 1984;110:643–8.
6. Schalin-Karrila M, Mattila L, Jansen CT, et al. Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandis. Brit J Dermatol 1987;117:11–19.
7. Lovell CR, Burton JL, Horrobin DF. Treatment of atopic eczema with evening primrose oil. Lancet 1981;I:278 (letter).
8. Wright S, Burton JL. Oral evening-primrose oil improves atopic eczema. Lancet 1982;ii:1120–22.
9. Morse PF, Horrobin DF, Manku MS, et al. Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response. Brit J Dermatol 1989;121:75–90.
10. Bamford JTM, Gibson RW, Renier CM. Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids). J Am Acad Dermatol 1985;13:959–65.
11. Horrobin DF, Stewart C. Evening primrose oil in atopic eczema. Lancet 1990;I:864–5.
12. Cornbleet T. Use of maize oil (unsaturated fatty acids) in the treatment of eczema. Arch Dermatol Syph 1935;31:224–34.
13. Hansen AE, Knott EM, Wiese HF, et al. Eczema and essential fatty acids. Am J Dis Child 1947;73:1–18.
14. Bjorneboe A, Soyland E, Bjorneboe G-E A, et al. Effect of dietary supplementation with eicosapentaenoic acid in the treatment of atopic dermatitis. Brit J Dermatol 1987;117:463–9.
15. Soyland E, Rajka G, Bjorneboe A, et al. The effect of eicosapentaenoic acid in the treatment of atopic dermatitis. A clinical Study. Arch Derm Venereol (Stockh) 1989;144(Suppl):139.
16. Olsen PE, Torp EC, Mahon RT, et al. Oral vitamin E for refractory hand dermatitis. Lancet 1994;343:672–3 (letter).
17. Anonymous. Severe atopic dermatitis responds to ascorbic acid. Med World News April 24,1989;41.
18. Finley EB, Cerklewski FL. Influence of ascorbic acid supplementation on copper status in young adult men. Am J Clin Nutr 1983;37:553–56.
19. Sheehan MP, Atherton DJ. One-year follow up of children treated with Chinese medical herbs for atopic eczema. Br J Dermatol 1994;130:488–93.
20. Sheehan MP, Rustin MHA, et al. Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis. Lancet 1992;340:13–17.
21. Evans FQ. The rational use of glycyrrhetinic acid in dermatology. Br J Clin Pract 1958;12: 269–79.
22. Laux P, Oschmann R. Witch hazel – Hamamelis virgincia L. Zeitschrift Phytother 1993;14: 155–66.

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Last revised: June 07, 2004

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